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10.1371/journal.pone.0069010 30 EgeciogluE.SteenslandP.FredrikssonI.FeltmannK.EngelJ

And in the randomized trials of these GLP-1 medications, about 14% to 38% of participants didn't achieve at least 5% weight loss

J Biol Chem 278:85168525

Together and especially if two or three show up at once with no other clear explanation they're worth paying attention to

While lisdexamfetamine does not directly affect glucose, appetite suppression and reduced food intake could increase hypoglycaemia risk in this context