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doi: 10.1111/dom.14166 [DOI] [PubMed] [Google Scholar] 65.Nakatani Y, Maeda M, Matsumura M, et al
A previous mediation analysis of semaglutide in adults with overweight or obesity suggested that less than one percentage point of the body weight reduction achieved with subcutaneous semaglutide was attributable to gastrointestinal adverse events (246)
A few things to note about this study is that there was no significant increase in risk for people after three years on these medications
For extra help, Gupta says most people are OK to use a gentle laxative or stool softener
If left untreated, many patients die between the ages of two and three years
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