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The best available published figure, from Jastreboff et al., NEJM 2023 , reported 24.2% body-weight reduction at 48 weeks on the 12 mg dose in a phase 2 trial

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Kristensen SL, Rorth R, Jhund PS, et al

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Researchers are also investigating its role in hyperhomocysteinemia and atherosclerosis

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3 Centre for Infection, Immunity and Inflammation, Ottawa, Ontario, Canada

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The metabolites were dissolved by liquid chromatography using mobile phase A and then separated via ExionLC Series UHPLC

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