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6 Additionally, downregulation of ER-alphawhich is metabolically more activeand downregulation of ERs during menopause increase fat accumulation in women, leading to weight gain

It is a critical safety protocol

For high-burden nations like India, the opportunity extends to prevention: pairing affordable drugs with community programs could bend the curve on obesity-driven diabetes

Using both reverse genetic and pharmacological approaches, we have demonstrated that TGR is an essential and druggable target for the treatment of schistosomiasis 18,19,20

It affects not only his health but also his activity level, energy, and overall quality of life