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Nitric oxide (NO) may decrease oxygen consumption by inhibiting several mitochondrial enzymes, including aconitase, electron transport chain complexes I and II, and cytochrome oxidase 53

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Another study using the CIA mouse model also suggested that Clostridium cluster XIVa can activate transforming growth factor- (TGF-), thereby enhancing the immunosuppressive function of Tregs (125)

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Factor(s) released from irradiated B-CLL cells induce apoptosis in leukemic lymphocytes