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In MetS, events such as increased oxidative stress and inflammatory cytokines generated by hyperglycemia and obesity can cause vascular endothelial dysfunction, compromising the vasomotor balance and increasing the adhesion of leukocytes to the endothelium in various organs and tissues, including the central nervous system (CNS) [7,8,9]

10.1016/j.biopha.2022.113402 113 YagodaN.von RechenbergM.ZaganjorE.BauerA

Bariatric surgery is an effective option for patients with BMI 40 kg/m or 35 kg/m with obesity-related complications

When used in medication form, such as semaglutide (found in products like Ozempic and Wegovy), GLP-1 can help reduce cravings, support insulin sensitivity, and assist in gradual, healthy weight loss

For many users, this translates into reduced appetite and, consequently, weight loss