- when there is risk of torsades de pointes, for example in patients with prolonged QT, concomitant administration of other medications that produce torsades de pointes (amiodarone, quinidine, bepridil, IV erythromycin, halofrantine, pentamidine, sparfloxacin, sultopride, vincamine, betrilio, disopyramide, sotalol, etc)
All potential benefits therefore must be weighed cautiously, and treatment is undertaken under medical supervision given that safety and efficacy are not yet established by regulatory authorities
J Neurol Neurosurg Psychiatry 51: 745752
Bacterial growth becomes possible despite bacteriostatic water
Lack of organelles and therefore the mitochondria-associated apoptotic machinery has raised concerns that highly specialized terminally differentiated RBCs can undergo apoptosis