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Currently, excessive NNMT upregulation is implicated in several scenarios, including obesity, metabolic diseases, muscle cell degeneration, and even some types of cancer [2, 4]

instead, it's a powerful agent for modulating the physiological drives behind eating

While marketed as a fat-burning peptide, its effectiveness in humans has not been scientifically confirmed

Theres a black market production, primarily in China, that sends large amounts of these peptides to the United States with the label For research only, says Pinchas Cohen, MD, dean and distinguished professor of gerontology, medicine, and biological sciences at the USC Leonard Davis School of Gerontology, who has discovered several investigational peptides

Nov 11 2025;26(1):250