[DOI] [PMC free article] [PubMed] [Google Scholar] 48
Retatrutides Phase 2 data suggest that the addition of a third receptor target may extend the efficacy ceiling further still, though direct head-to-head trials would be needed to draw firm comparative conclusions
School of Pharmacy, Pharmacy Australia Centre of Excellence, the University of Queensland, Woolloongabba, Queensland 4102, Australia
This is because the metformin component is cleared by the kidneys, and impaired function can lead to a buildup of the drug, increasing the risk of lactic acidosis
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