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218,219 9 The Consequences of Untreated Hearing Loss The ability to convert mechanical sound waves into electrical signals that travel to and are interpreted in the brain is a vital function, and hearing loss can lead to several important neurological changes

Third, the main limiting factor is that the main CNS pharmacokinetic principles are not followed during the evaluation of drug delivery efficacy of nanocarriers and (pro)drugs, which leads to inaccurate interpretation of the results or inadequate investigation of the brain delivery of drugs

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2013 Jul 10;31(20):2627-33