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Description

Shock occurred in 75 percent of the children and 51 percent had clear myocardial impairment

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While MPNST remains a challenging malignancy, several promising advances are underway: MEK Inhibitors in NF1-Associated MPNST Given the dysregulation of the RAS/RAF/MEK pathway in NF1-related tumors, MEK inhibitors like selumetinib have shown efficacy in benign plexiform neurofibromas

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doi: 10.1107/S0907444912001308 3 Ayoub MoubareckC.Hammoudi HalatD

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