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However, considering GHKs high affinity for copper (see below) and essentiality of copper for cell growth, it is virtually impossible to have copper-free GHK in a living system

NAD+ supports the core energy production and repair machinery , while MOTS-C acts as a regulatory signal that shifts metabolism efficiently in response to stress and energy demand

Proc Natl Acad Sci USA 86: 13981400

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