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0.1% (placebo) Steady State: Achieved after 4-5 weeks of weekly dosing Safety: Nausea (68% at 4.5 mg), vomiting (32%), generally mild-moderate and transient Discontinuation: 14% discontinued due to GI adverse events Appetite Effects: Significant reductions in Visual Analogue Scale (VAS) hunger scores Publication: Lau DCW, et al

Crucial for bone health during weight loss

Storage:Protected from direct light and humidity at a temperature of 35.6-46.4F (2-8C)

Whilst B12 injections are well-established NHS treatments for documented deficiency, lipotropic combinations lack robust clinical evidence and are not routinely prescribed within the NHS

6 Changes in plasma concentrations triiodothyronine (T 3 ) and thyroxine (T 4 )