Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice
A recent review confirmed that at OTC doses, ibuprofen has a low incidence of serious gastrointestinal (GI) events and minimal risk of causing renal and associated cardiovascular events, among others
I would generally recommend, however, that you do both things simultaneously because I dont see the benefit in waiting if you are symptomatic
For a broader look at common treatment reactions, see our GLP-1 side effects guide
Oral collagen supplements may take the form of a beverage, capsules, powder, gel, tablets, gummies, or protein bars