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[38] Although initial reports suggested mildronate is a non-competitive and non-hydroxylatable analogue of gamma-butyrobetaine, [39] further studies have identified mildronate is indeed a substrate for gamma-butyrobetaine dioxygenase

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NRP1 structure/function NRPs are single-pass transmembrane, non-tyrosine kinase surface glycoproteins, expressed by endothelial, immune, and vascular smooth muscle cells and are regulators of numerous signaling pathways within the vasculature 313,314

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