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Citation13,Citation39 Citation43 Notes : The enzymes are glyceraldehyde 3-phosphate dehydrogenase in the glycolytic pathway, pyruvate dehydrogenase complex catalyzing the formation of acetyl-CoA from pyruvate, and the isocitrate dehydrogenase, -ketoglutarate dehydrogenase, and malate dehydrogenase in the Krebs cycle

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Different from regular cancer cells, CSCs have a lower level of ROS, which might contribute to a slower growth rate, reduced oxidative metabolism, and elevated expression of the ROS scavenging system (Bystrom et al., 2014

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