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Design Single-center, retrospective, observational study

There is a pressing need for standardized diagnostics and longitudinal studies to clarify the temporal relationship between microbiome changes and disease onset, as well as to identify reliable microbial or metabolic biomarkers for early detection and targeted intervention (Dai et al., 2024

Mn overexposure led to increased expression of proteins in the ER stress pathway, while ER stress inhibitor reduced Mn-induced apoptosis (Liu et al., 2020)

A: Most users notice improved hydration and subtle radiance within the first week

In cosmetic products, it has been found to tighten loose skin and improve elasticity, skin density, and firmness, reduce fine lines and wrinkles, reduce photodamage and hyperpigmentation, and increase keratinocyte proliferation, which plays a crucial role in skin health and regeneration