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Cascone T, Sepesi B, Lin HY, Kalhor N, Parra ER, Jiang M, Godoy MCB, Zhang J, Fossella FV, Tsao AS, Lam VK, Lu C, Mott FE, Simon GR, Antonoff MB, Mehran RJ, Rice DC, Behrens C, Weissferdt A, Moran C, Vaporciyan AA, Lee JJ, Swisher SG , Gibbons DL, Wistuba II, William WN Jr, Heymach JV

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MC5R: Expressed in multiple tissues, its exact physiological role remains relatively undefined, although it is believed to be involved in exocrine function

Applying an ice pack or cold compress may also bring relief

The answer depends on the patients overall health, dialysis status, and medical history