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Use caution when prescribing CONTRAVE to patients with an elevated risk of seizure, including: history of head trauma or prior seizure, severe stroke, arteriovenous malformation, central nervous system tumor or infection, or metabolic disorders (eg, hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia)

FDA does not verify the safety, effectiveness, or quality of compounded drugs before they are marketed." Compounding pharmacies are licensed facilities that prepare customized medications for individual patients based on prescriptions from licensed healthcare providers

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