Study methods: Adult patients who were taking GLP-1s and scheduled to receive anesthesia at 3 hospitals between June 30, 2023, and August 15, 2024, were evaluated via preoperative point-of-care gastric ultrasonography (GUS)
Luo D, Zhang JB, Li SP, Liu W, Yao XR, Guo H, Kim NH Imperatorin ameliorates the aging-associated porcine oocyte meiotic spindle defects by reducing oxidative stress and protecting mitochondrial function
The redox properties of NADs regulate the direction of hundreds of cellular biosynthetic pathways varying from amino acid, lipid and nucleotide synthesis to folate cycle, detoxification reactions of drugs and reactive oxygen species 57
Canadian protocols and clinical evidence
But the mechanistic rationale is strong, and early anecdotal reports from researchers and clinics using the combination suggest meaningful improvements in appetite control, energy expenditure, and overall metabolic response compared to retatrutide alone