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Metabolic syndrome, characterized by a group of cardiovascular risk factors, including insulin resistance, high blood pressure, high blood glucose levels, low HDL cholesterol levels, high triglyceride levels, and abdominal obesity, is associated with increased cholesterol secretion and gallstone formation (Shabanzadeh, Skaaby, Sorensen, Eugen-Olsen 2017

Thus, subjects with vascular disease may have decreased ability to achieve and maintain an erection

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