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Under hypoxic (5%O 2 ) conditions, high expression of HIF-1 and VEGF was observed in mouse submandibular gland tissues, while HIF-1 mediated by BAY87-2243 inhibited salivary gland development (195)

Doping in sport and regulatory response Meldonium's classification as a prohibited substance was catalyzed by evidence of widespread systemic use, most notably at the 2015 Baku European Games (61, 62)