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Less pronounced than GHRP-6

Strengths Acts via multiple pathways (GLP-1, AMPK, microbiome) Has existing human data showing reductions in fasting glucose, HbA1c, lipids Support receptor expression and islet health Limitations Low absorption and bioavailability Gastrointestinal discomfort is common (diarrhea, cramping)

2022;322(5):H81941

Other protein sources, such as nuts, seeds, grains and beans, contain some but not all essential amino acids and are therefore referred to as incomplete

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