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Los estudios en animales han mostrado riesgos potenciales para el desarrollo fetal, y los datos en humanos an son limitados

ALP, osteocalcin, type I collagen, Runx2, and osterix are examples of osteoblast differentiation indicators whose mineralization and expression are inhibited by rutin treatment, whereas adipogenic markers are increased (134)

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24 The uncontrolled proliferation and migration of vascular smooth muscle cells (VSMCs) are touted as one of the risk factors resulting in atherosclerosis