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At 10mg, clinical trials showed 21.4% average body weight loss, approximately 49 pounds from a 230-pound starting weight

The evidence supports their safety in psychiatric populations

Subjects with obesity and diabetes appear to be at an even higher risk for depression compared to subjects with obesity but not diabetes [12]

endoscopy procedures could not be performed, and a repeat attempt was scheduled after 36 hours on an empty stomach

Whatever the perspectives brought to bear on further studies of MS, it is clear these will require large sample sizes and longer periods of study in order to adequately define benefit