Although some of the natural ingredients used in these patches, such as berberine, have shown in some studies to slightly increase GLP-1 levels, regulate blood sugar levels and promote weight loss 8 , their efficiency through transdermal methods is not yet proven and needs to be studied further 3
It is usually well tolerated
For example, as a whole, peptide therapy grew in year-over-year popularity by 281% on Google, 459% on TikTok and 412% on Instagram as of early April of this year, according to Alyssa Williams Atkinson, category insights manager at Spate market research
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The effect of Ex-4 on chow-induced AgRP neuron inhibition was dose dependent (Supplemental Figure 5, IP), consistent with dose-dependent effects of GLP-1 analogs on food intake (24)