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In addition, reduction of inflammatory factors, reduction of angiotensin II, and improvement of blood sugar and blood pressure by GLP-1RAs have been suggested as mechanisms of kidney protection effect

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El ajuste post hoc para HbA1C y otros factores de riesgo renal tradicionales no tuvo una influencia importante en el beneficio renal con liraglutida, semaglutida o dulaglutida en los CVOT, ni hubo diferencias en el control glucmico en el estudio AWARD-766

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5.2.2 Future perspectives Conducting well-designed multiple clinical trials specifically focused on the use of SGLT2 inhibitors in cancer treatment is imperative