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TB 500: 25 mg weekly, often used systemically

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The Ras, Rho/Rac, and Rab families of GTPases, key modulators of cellular signaling, cytoskeletal dynamics, organelle membrane remodeling, and vesicular transport, contain various C-terminal cysteine motifs that must be isoprenylated for proper membrane localization and function [73,74]

NIM 27:8086

These data are particularly interesting since earlier stimulation studies support the role of DBS in promoting neurogenesis through findings that electrical fields can (1) selectively direct the migration of stem cells [377,378,379], (2) increase blood flow [380], and (3) modulate neural networks (see sections by Cooperrider, Manto and Oulad Ben Taib, Bradnam and McCambridge, Popa and Hallett, and Timmann and Nitsche)