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And the protocol for missed tirzepatide doses is clearly defined

The titration process typically spans 16 weeks, with dose increases every four weeks to allow adjustment to each new level

Nausea may increase slightly as the dose doubles, but the B12 component and slow escalation help manage it

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The study utilized Cox proportional hazards and Kaplan-Meier survival analyses to assess the risk differences, reporting hazard ratios (HRs), and 95% confidence intervals (CIs)