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Scientific Reports, 13 , 16879

These contraindications are expected to mirror those of existing GLP-1 medications, though the final prescribing information will be determined after FDA review

IBD patients with reduced Fas expression on intestinal lamina propria (LP) T-cells and macrophages may have a reduced susceptibility to Fas/FasL-mediated apoptosis (61)

Side effects for tirzepatide are also similar to those for semaglutide and include mild and manageable GI issues like nausea, vomiting, diarrhea, and constipation