Effect of Spironolactone on Kidney Function in Kidney Transplant Recipients (the SPIREN trial): A Randomized Placebo-Controlled Clinical Trial Line A Mortensen, Bente Jespersen, Anne Sophie L Helligsoe, Birgitte Tougaard, Donata Cibulskyte-Ninkovic 3, Martin Egfjord, Lene Boesby, Niels Marcussen, Kirsten Madsen, Boye L Jensen, Inge Petersen, Claus Bistrup, Helle C Thiesson PMID: 38416033 The SPIREN trial was a double blind RCT done at 4 Danish centres, comparing spironolactone to placebo in 180 kidney transplant recipients
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This atrophy can permanently affect the strength and coordination of the hand, limiting fine motor skills and reducing overall hand functionality
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E G Quantitative analyses of MDA, GSH, and non-heme iron