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When SCFAs, a metabolite of GM, were supplemented to antibiotic-treated mice, IGF-1 and bone mass were restored to the levels of normal mice, suggesting that the restoration of the GM in germ-free mice induces circulating levels of IGF-1 through the production of SCFAs, which in turn affects bone metabolism (Yan et al., 2016)

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2014;99(2):40822 Cheungpasitporn W, Thongprayoon C, OA OC, Edmonds PJ, Kittanamongkolchai W, Erickson SB

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The interplay between decreased neurotrophic support and increased apoptosis is critical for understanding the development of depressive symptoms in individuals with chronic alcohol use

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