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Several complex signal transduction pathways and cellular processes have been implicated in APAP hepatotoxicity, including those involving c-Jun N-terminal kinase, Nuclear factor E2-related factor 2 (Nrf2), p53, endoplasmic reticulum stress, autophagy, and sterile inflammation (Chowdhury et al

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However, some studies have reported neutral or negative mood effects, underscoring the need to understand individual variability

Emerging Strategies to Treat Rare and Intractable Subtypes of Melanoma

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