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Category 2 designation means the FDA identified these substances as presenting potential safety concerns and deemed them not currently eligible for routine compounding under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act

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Figure 3 This study represented a milestone since it ended the 10 year development of the concept of using DPP-4 inhibition for glucose-lowering action in type 2 diabetes with a clear proof-of-concept study