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Johns Wort may affect how doxycycline is metabolized, potentially lowering its effectiveness

Long-term safety should be assessed by your prescribing provider

Basis for Warning: This warning is based on findings in rodent studies, where semaglutide (and other GLP-1 RAs) caused a dose-dependent and treatment-duration-dependent increase in the incidence of these tumors

Contact your provider if nausea persists beyond 12 weeks or if you experience severe abdominal pain

In clinical trials, approximately 50% of participants achieved at least 15% body weight reduction, and roughly 30% achieved 20% or greater reduction at the highest doses