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No dose adjustment is required for hepatic impairment, though limited data exists for severe cirrhosis and specialist input should be sought for decompensated disease

References 1 De VriesJMichielsenHVan HeckG

Many people pursuing aggressive weight loss wonder if stacking semaglutide with phentermine could accelerate results, but this combination carries significant risks that doctors rarely recommend together

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There is time to discuss whether a GLP-1 makes sense for your specific situation, monitor side effects, manage dose escalations, and adjust if something is not working