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So when one of our physicians or nurse practitioners sees a patient with obesity and we are prescribing, deprescribing, managing side effects or addressing abnormal laboratory values, we work with the PCP, we communicate with the PCP to try to create a coordinated approach so that the patient is getting excellent primary care to address the multitude of clinical conditions that they may have, while also receiving excellent specialty care to manage this underlying complicated disease state

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For those who follow a vegetarian or vegan diet, fortified foods or supplements may be necessary

VKTX would be a speculative position within a portfolio with additional de-risking data required following additional trials (slower titration for improved tolerability and TEAEs, increasing efficacy over longer duration, maintenance ability) to possibly allow for a more generous sizing/position

Although GI AEs are common across all GLP-1 RAs, differences in formulation, dosing, and dual agonism with tirzepatide can influence how well patients tolerate therapy