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Thyroid hormones exhibit profound metabolic effects characterized by an increased rate of both catabolic and anabolic reactions, resulting in an overall acceleration of the basal metabolism which is associated with increased oxygen consumption, respiratory rate, energy expenditure, and heat production (56)

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Kashyap PC, Marcobal A, Ursell LK et al (2013) Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice

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These gene targets create powerful effects that researchers are particularly interested in especially how they translate into practical benefits for aging research