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United States Patent US8268372 (B2) Orumets K, Kevvai K, Nisamedtinov I, Tamm T, Paalme T (2012) YAP1 over-expression in Saccharomyces cerevisiae enhances glutathione accumulation at its biosynthesis and substrate availability levels

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Improvement at 3-month follow-up was defined as follows: Urinary improvement: reduction in frequency or resolution of urinary urgency or incontinence episodes based on patient report and clinician assessment