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Mood stabilising drugs increase CaMKK2 activity and abundance Mood stabilisers are a class of drugs that are used to treat and manage both the manic and depressive phases of bipolar disorder [159]

Consistent with this, exendin-P5, which induces faster kinetics in G protein activation and cAMP production, exhibits higher cAMP efficacy than GLP-1 and exendin-4, as indicated by a greater pEC 50 /pIC 50 ratio when comparing cAMP and binding studies 13

Quadri P, Fragiacomo C, Pezzati R, Zanda E, Forloni G, Tettamanti M, Lucca U (2004) Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, alzheimer disease, and vascular dementia