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As noted by experts at the University of Connecticut, GLP-1 peptide molecules are too large to effectively penetrate the skin barrier, making transdermal delivery of actual GLP-1 medications currently impossible with existing technology

Other developments in GLP-1 receptor agonism include the formation of small orally available agonists and compounds with the potential to pharmaceutically stimulate GLP-1 secretion from the gut

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Activities to Try: Longer walks with varied pace and/or uphill sections Light resistance training (using light weights, resistance bands or bodyweight-only exercises) Cycling (stationary or outdoor) Low-impact dance workouts Pilates or mat-based core and strength work For Those 4+ Months into GLP-1 Treatment Once you've been taking medication for a few months and your bodys adapted, you will probably start to see a decrease in your BMI and improved mobility