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428,429 HSPs are induced in response to various CNS pathologies, including neurodegenerative diseases, ischemia, and epilepsy, where they play a neuroprotective role by preventing protein aggregation and misfolding

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Specifically, to address the limitation raised by commenters regarding the use of MPNs to identify covered entities and providers affiliated with them, CMS will additionally engage in mapping 340B OPAIS-provided organizational NPIs to corresponding individual NPIs and MPNs using data sources such as the CMS Integrated Data Repository to establish a supplemental list of prescriber NPIs associated with covered entities

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