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In this study, to overcome the challenges in developing TYR-based therapeutics for skin disease treatments, we designed a multifaceted strategy to leverage the catalytic activity of TYR to generate therapeutics in situ through the CuAAC reaction

PMID: 31987229

While clinical interactions have not been documented, combining multiple compounds that affect similar pathways increases unpredictability

19: Johnson & Johnsons FGFR kinase inhibitor Balversa (erdafitinib) received full FDA approval Friday for locally advanced or metastatic urothelial carcinoma, converting an accelerated nod granted in April 2019

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