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The clinical spectrum is very heterogeneous, ranging from hypoketotic hypoglycemia, liver dysfunction, rhabdomyolysis, cardiomyopathy and early demise

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Prescription requirements exist because GLP-1 medications affect appetite signaling, blood sugar regulation, and cardiovascular function

Food and Drug Administration recently issued a warning against using unapproved GLP-1 drugs for weight loss, citing quality concerns, false or misleading labels, counterfeit drugs and more than 1,600 reports of adverse effects associated with compounded GLP-1 medications