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So ME/CFS is on the spectrum of POTS it's just that they haven't necessarily met the heart rate criteria for POTS

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Ishii H., Hansen B.B., Langer J., Horio H

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Endocrinology (2011) 152:29256.10.1210/en.2011-1385 55 SmithEPAnZWagnerCLewisAGCohenEBLiBet alThe role of beta cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs

In most cases, the medication will simply be less effective