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PMID: 11713213 3

Dec 2005;30(6):493-495

Panels A, B, and C show the percentage of surviving hepatocytes for females (blue curves) and males (red curves) for a 15 g dose, an 18 g dose of APAP, and a 30 g dose of APAP, respectively, over the first 80 h after ingestion

GPX4 is a core inhibitor that directly reduces the formation of lipid hydroperoxides during ferroptosis

Phase 3 (COSMIC-312) study of cabozantinib (C) in combination with ate zolizumab (A) versus sorafenib (S) in patients (pts) with advanced hep atocellular carcinoma (aHCC) who have not received previous systemic a nticancer therapy