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doi: 10.2147/CIA.S158513 85 KlaunigJE

Novo, which is known for its hit Wegovy and Ozempic injections for obesity and diabetes respectively, said the launch opens new possibilities for the more than 100 million Americans living with obesity

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This was first explored by Balthasar and colleagues, who in 2005 proved that specific inhibition of the IgG:FcRn interaction by use of a murine mAb (mouse IgG1, clone 4C9) with V regions specific for rat 2m generated by Bjorkman and colleagues could deplete endogenous IgG levels in rats [113, 114]