Samtiya M, Bhat MI, Gupta T, Kapila S, Kapila R (2020) Safety assessment of potential probiotic Lactobacillus fermentum MTCC-5898 in murine model after repetitive dose for 28 days (sub-acute exposure)
The recommended semaglutide dosing schedule, as per the prescribing information and clinical trials, is as follows: Administer WEGOVY once weekly, on the same day each week, at any time of day, with or without meals Inject subcutaneously in the abdomen, thigh or upper arm (alternate injection site) In 4 week intervals, increase the dose until a dose of 2.4 mg is reached
Response: We will consider this suggestion as we continue to refine this policy area
That is an incredibly small injection volume, less than 0.4 mL
During tissue granulation, fibroblasts form a bed of collagen by transforming into the myofibroblast phenotype, with an augmented alpha-smooth muscle actin (-SMA) cytoskeleton, which is critical for promoting Wound Healing (van de Water et al., 2013)