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Joseph Zucchi, PA-C, MPAS, is a board-certified physician associate specializing in obesity medicine and clinical supervisor at Transition Medical Weight Loss in Salem, New Hampshire

A: It is used mainly to help manage type 2 diabetes by improving blood sugar control

The major adverse effects of topical retinoids and topical vitamin C are local skin irritation, including erythema, peeling, dryness, burning and itching, which depend on the concentration and formulation of the product (129,130)

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Neither of these is easy to answer, and theres little data available right now