Study population The study included all adults aged 35 years or older who are regular VHA users (as defined by presence of at least one inpatient or outpatient medical encounter), with at least one set of vital signs, and one set of laboratory investigation (including glucose, glycated hemoglobin [HbA1c], serum creatinine, and lipid panel) during the baseline period
Semaglutide can feel like a slower start but steady progress
Among patients without CKD, minimal increases in serum creatinine were observed for patients on a GLP-1 compared to those who were not prescribed a GLP-1: 0.01 mg/dL for semaglutide, 0.01 mg/dL for liraglutide, and 0.02 mg/dL for tirzepatide
For those considering retatrutide versus tirzepatide dosage comparisons , the same principles apply
Research is needed to explore how these two approaches interplay, but the appetite-suppressing and insulin-regulating effects may work in tandem